Overview:
We are seeking a highly motivated and organized individual to join our dynamic team in a hybrid Research Associate (RA) / Lab Manager (Contractor) position. The contract is expected to last 6 months. This is an exciting opportunity to contribute to cutting-edge mRNA-based therapeutics while also playing a key role in the smooth operation of our lab facilities. You will be part of a rapidly growing startup working on novel programmable mRNA technologies to target diseases at the cellular level.

Key Responsibilities:

Research Associate Responsibilities (80%):

• Assist in cloning of high-content plasmid libraries and NGS sample prep for high-throughput screens, ensuring timely and efficient workflows.

• Design and perform molecular biology experiments, including plasmid cloning and sample preparation for RNA sequencing (RNAseq, RNA amplicon sequencing).

• Normalize plasmids and prepare new stocks and aliquots of common plasmids for ongoing experiments.

• Perform nucleic acid extraction, RT-qPCR, dPCR, and other molecular characterization assays.

• Collaborate with team members to analyze data and present findings in group meetings.

• Maintain comprehensive, organized lab notebooks and experiment documentation.

Lab Management Responsibilities (20%):

• Oversee the scheduling and maintenance of laboratory equipment, ensuring proper calibration and functionality.

• Ensure laboratory equipment is in optimal condition (e.g., MiSeq sequencer, Attune flow cytometer).

• Manage inventory and ordering of laboratory consumables, ensuring stocks are adequately replenished.

• Prepare media for tissue culture (TC) and oversee other common laboratory preparations.

• Perform routine autoclaving of water and other necessary materials.

• Manage incoming shipments, including picking up packages from the loading dock, un-boxing, and organizing the lab space.

• Maintain accurate records of lab activities, inventory, and equipment status.

Qualifications:

• B.S. or M.S. in Biology, Bioengineering, Genetics, or related field.

• 5+ years of laboratory experience (academic or industry), with a strong foundation in molecular biology techniques.

• Strong organizational and multitasking skills, with an ability to maintain efficient lab operations and manage competing priorities.

• Familiarity with maintaining lab equipment, inventory systems, and ordering procedures.

• Excellent communication skills with the ability to present scientific data clearly and concisely.

• Positive, proactive, and collaborative team player with the ability to work independently.

Preferred Qualifications:

• Experience with flow-cytometry highly preferred

• Experience in cloning, plasmid preparation, and sample prep for RNAseq.

• Experience with high-content pooled libraries

• Experience with mammalian tissue culture, including BSL2 practices, transfection, and reporter assays.

• Prior experience with lab management, inventory control, and maintaining lab safety protocols.

• Familiarity with lentiviral production or mRNA-based production systems.

How to Apply:
We offer a competitive salary and the chance to work with an innovative, passionate team in a fast-paced startup environment. If you are excited to contribute to groundbreaking science and play an integral role in lab operations, we encourage you to apply.