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Molecular Biology Research Associate

Neptune Bio

Neptune Bio

New York, NY, USA
Posted on Mar 13, 2024

With a rapidly growing team of single-cell biologists, genome engineers and deep learning enthusiasts, backed by top-tier TechBio investors. Our exciting early stage biotech, Neptune Bio, aims to efficiently engineer sustainable cell state transitions for complex phenotypes and disease. We combine massively scalable high-content single-cell screening and multimodal large language foundation models to identify the best therapies at scale, no matter the combinatorial complexity. Founded in 2023 by Rahul Satija, Harm Wessels, Yuhan Hao and Ben Van de Graaf, Neptune Bio is led by an excellent team of lead scientists in single-cell biology and method development, genome engineering, and experienced operations. The science behind these platforms has been published in leading journals including Cell, Nature Biotechnology and Nature Methods.

Position Summary

This position offers the opportunity to work in a multidisciplinary team on cutting-edge technologies at the intersection of cell biology, genome engineering and single-cell multiomics. Responsibilities include a variety of techniques such as, molecular biology, Next Generation Sequencing library preparation, as well as cell culture or flow cytometry. The role will expose the successful candidate to a wide range of wet-lab techniques and will foster their growth through close collaborations with PhD-level scientists. The successful candidate will be an excellent team player and a diligent experimental biologist who can thrive in a fast-paced startup environment.

Key Responsibilities

  • Next Generation Sequencing amplicon library preparation
  • Single-cell RNA-seq library preparation
  • Molecular cloning and testing of constructs for genome engineering
  • Assisting with large scale bulk and single-cell screening
  • Cell culture (Maintaining and testing established cancer cell lines)
  • Maintaining key instruments
  • Keeping a detailed record of experimental procedures and results
  • Placing orders and maintaining the inventory

Qualification and Education Requirements

You must have:

  • Bachelor’s or Master’s degree in Biology, Biochemistry, Chemical Engineering, Biomedical Engineering, or a related field
  • 2+ years of full-time wet lab experience (industry or academia)
  • Experience with Single-cell Biology (i.e. 10x Genomics or sciRNA-seq) and Next Generation Sequencing library preparation
  • Experience with standard molecular and cell biology techniques (plasmid design, cloning, PCR)
  • Experience with mammalian cell culture
  • Willingness to quickly discover and learn new methods and approaches
  • Ability to adjust rapidly to shifting priorities and deliver high-quality, detail-oriented results in a timely manner
  • Teamwork and collaborative attitude are essential
  • Strong organizational and record-keeping skills
  • Critical thinker with excellent communication skills who thrives in a multidisciplinary fast-paced team environment

Additional preferred experience includes:

  • Industry experience, specifically in biotech
  • Experience with primary immune cell isolation and culture or organoid models
  • Experience with CRISPR-Cas systems, gene editing and delivery technologies
  • Experience with CRISPR screening