Faeth Therapeutics is a clinical-stage oncology company listed on Nasdaq that recently raised $200M in funding. With a strong scientific foundation and a founding team that includes the discoverer of our target pathway, we are advancing PIKTOR, a multi-node PI3K/AKT/mTOR inhibitor program, toward multiple near-term milestones. We are a small, focused team where every person has direct impact — united by a shared commitment to care deeply, create boldly, and never stop learning.

We are seeking a highly motivated Postdoctoral Scientist/Senior Scientist to join our preclinical R&D team in Cambridge, UK. You will contribute directly to therapeutic development within a fast-moving biotech environment. This is a hands-on, laboratory-based role focused on mechanistic biology / biochemistry and the translation of basic science to clinical interventions. You will play a key role in developing and advancing existing clinical and preclinical programs, identifying and validating novel drug targets by design / execution of high-impact experiments across in vitro and in vivo systems.

Characteristics

• Rigorous and curious experimental scientist with a strong focus on mechanistic biology
• Highly flexible and collaborative with ability to switch easily between projects and tasks in a dynamic way based on company priorities
• Mission-driven, with a clear motivation to translate discoveries from bench to patient impact
• Comfortable operating in a fast-paced, results-oriented environment
• Highly organised, with strong attention to detail and data integrity
• Resilient and motivated to solve challenging scientific problems
  
  

Qualifications / Core Skills & Experience

• PhD in a relevant life science discipline ideally with additional postdoctoral experience in academia or industry
• Strong expertise in core molecular biology / biochemistry techniques
• Proven ability to design and execute experimental programs independently
• Excellent record-keeping and scientific communication
  
  

Desirable Skills & Experience (strong candidates are expected to have some, not all)

• Experience in cancer models / development of (cancer) therapeutics
• Experience designing and supervising in vivo (mouse) model experiments
• Experience in cellular metabolism or metabolic biology
• Protein production - expression and purification of recombinant proteins from mammalian and bacterial systems
• Assay development - Design and optimisation of biochemical and biophysical assays to profile compound-target interactions
• Familiarity with kinetic analysis and enzyme mechanisms
• Organoid or 3D cell culture systems
• Understanding of PK/PD principles
• Programming/data analysis (e.g. R, Python)
  
  

Additional Information

• Location: Cambridge, UK (full time on-site wet lab role)
• Compensation: Competitive salary + equity incentive + bonus
• This role is subject to a 6-month probationary period
  
  

We are an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.